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	Provedor de dados Biol. Res. (2) Autor Chaves,Mariana H (2) Bezerra,Roosevelt D S (1) Carneiro,Sabrina M. P (1) Carvalho,Fernando A. A (1) Fernandes,Hélio B (1) Meneses Oliveira,Rita C (1) Neto,José M. M (1) Oliveira,Francisco A (1) Passos,Flávia Franceli B (1) Santana,Lorena C. L. R (1) Silva,Francilene V (1) Sousa,Alessian P. L (1) Mais... Palavra-chave Anti-leishmanial (1) Antioxidant (1) Azadirachta indica (1) Cytotoxicity (1) Ethanol (1) Gastroprotection (1) Leishmania amazonensis (1) Leishmaniasis (1) Nitric oxide (1) Parkia platycephala (1) Ulcer (1) Mais... Tipo do documento Journal article (2) Ano 2012 (1) 2010 (1) País Chile (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Gastroprotective effect of the ethanolic extract of Parkia platycephala Benth. leaves against acute gastric lesion models in rodents Biol. Res. Fernandes,Hélio B; Silva,Francilene V; Passos,Flávia Franceli B; Bezerra,Roosevelt D S; Chaves,Mariana H; Oliveira,Francisco A; Meneses Oliveira,Rita C. Parkia platycephala Benth. (Leguminosae - Mimosoideae), popularly known as "visgueira", fava bean tree or "fava-de-bolota", is widely found in the Northern and Northeastern regions of Brazil. Its pods are used as cattle food supplement in the drought period. Compounds with a gastroprotective activity were obtained from the genus Parkia. Therefore, this study aimed at investigating the gastroprotective effect of the ethanolic extract of Parkia platycephala Benth. leaves (Pp-EtOH), as well as evaluating its possible mechanisms of action in experimental ulcer induction models. Lesions were induced by absolute ethanol, ethanol-HCl, ischemia-reperfusion and indomethacin in rodents. Pp-EtOH showed a protective effect in the lesion models (66, 48 and 52 %,... Tipo: Journal article Palavras-chave: Antioxidant; Ethanol; Gastroprotection; Nitric oxide; Parkia platycephala; Ulcer. Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400010 The cytotoxic and antileishmanial activity of extracts and fractions of leaves and fruits of Azadirachta indica (A Juss.) Biol. Res. Carneiro,Sabrina M. P; Carvalho,Fernando A. A; Santana,Lorena C. L. R; Sousa,Alessian P. L; Neto,José M. M; Chaves,Mariana H. The leishmaniases are severe parasitic diseases that occur worldwide, caused by protozoa of the genus Leishmania. Studies with medicinal plants can lead to a range of possibilities for treating and improving the patients' quality of life. Research on Azadirachta indica fractions and extracts has shown that they have excellent anti-leishmanial activity based on bioactivity-guided fractionation of ethanolic extracts of leaves and seeds and in vitro activity against promastigotes. In this research the most efficient extracts and fractions were selected for tests on intracellular amastigotes of Leishmania amazonensis. The ethanolic extract of the leaves and dichloromethane and chloroform fractions had IC50 values of 38, 3.9 and 1.2 μg/mL for... Tipo: Journal article Palavras-chave: Anti-leishmanial; Azadirachta indica; Cytotoxicity; Leishmaniasis; Leishmania amazonensis. Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000200002 Registros recuperados: 2 Primeira ... 1 ... Última

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