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Histomorphometric and Immunohistochemical Study of Early Adaptative Response of the Vascular Wall in a Termino-Terminal Microsurgical Model of Femoral Vessels in Wistar Rat International Journal of Morphology
Velazquez-Gauna,Sergio E; Soto-Domínguez,Adolfo; Quiroga-Garza,Alejandro; Reyes-Hernández,Cynthia G; Chavez-Reyes,Arturo; Morales-Avalos,Rodolfo; Montes-de-Oca-Luna,Roberto; Guzmán-López,Santos; Elizondo-Omaña,Rodrigo E.
When a vein segment is grafted into arterial circulation, biomechanical forces stimulate modification of its structure. This morphological adaptive response is progressive during a medium or long term and occludes the vessel lumen, leading to a graft failure. The objective of this study was to characterize the early morphological response of the vascular wall in a terminal-terminal vascular vein graft model in Wistar rats. A segment of the femoral vein was placed in the femoral circulation. An end to end microsurgical graft anastomosis technique was implemented and standardized in twenty rats. The samples were processed with histological technique to analyze the overall structure with hematoxylin and eosin, the composition of the vessel wall with Masson...
Tipo: Journal article Palavras-chave: Hyperplasia; Morphology; Microsurgical model; Vascular adaptive changes; Venous graft.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200016
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