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	Provedor de dados BJID (2) BJPS (1) Autor Chen,Li (3) Gan,Jian-He (1) Ge,Guo-Hong (1) Ge,Guo-hong (1) Guan,Fengying (1) Li,Kun (1) Niu,Zhi-Lin (1) Peng,Pen-li (1) Sun,Li (1) Tan,You-Wen (1) Tan,You-wen (1) Yang,Li-Jun (1) Yu,Xue- Jun (1) Zhang,Dong-Jun (1) Zhang,Ping (1) Zhao,Wei (1) Zhao,Yun (1) Zhou,Xing-bei (1) Mais... Palavra-chave Adenosine deaminase analysis (1) Anti-viral therapy (1) Chronic hepatitis B (1) Heroin analysis (1) Mutations (1) Purine nucleotide/effects/brain rats (1) Purine nucleotide/quantitative analysis (1) Xanthine oxidase analysis (1) YMDD (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Ano 2016 (1) 2014 (1) 2012 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Efficacy of Entecavir therapy in elderly patients with chronic hepatitis B infection BJID Tan,You-wen; Ge,Guo-hong; Sun,Li; Zhou,Xing-bei; Peng,Pen-li; Chen,Li. Tipo: Info:eu-repo/semantics/other Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000600691 YMDD motif mutations in chronic hepatitis B antiviral treatment naïve patients: a multi-center study BJID Tan,You-Wen; Ge,Guo-Hong; Zhao,Wei; Gan,Jian-He; Zhao,Yun; Niu,Zhi-Lin; Zhang,Dong-Jun; Chen,Li; Yu,Xue- Jun; Yang,Li-Jun. OBJECTIVE: This study aimed to determine the natural prevalence of variants of tyrosine-methionine-aspartic acid-aspartic acid (YMDD) motif in patients with chronic hepatitis B (CHB), and to explore its relation with demographic and clinical features, hepatitis B virus (HBV) genotypes, and HBV DNA levels. METHODS: A total of 1,042 antiviral treatment naïve CHB patients (including with lamivudine [LAM]) in the past year were recruited from outpatient and inpatient departments of six centers from December 2008 to June 2010. YMDD variants were analyzed using the HBV drug resistance line probe assay (Inno-Lipa HBV-DR). HBV genotypes were detected with polymerase chain reaction (PCR) microcosmic nucleic acid cross-ELISA, and HBV deoxyribonucleic acid (DNA) was... Tipo: Info:eu-repo/semantics/article Palavras-chave: YMDD; Mutations; Chronic hepatitis B; Anti-viral therapy. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300006 Effects of purine nucleotide administration on purine nucleotide metabolism in brains of heroin-dependent rats BJPS Li,Kun; Zhang,Ping; Chen,Li; Guan,Fengying. ABSTRACT Heroin is known to enhance catabolism and inhibit anabolism of purine nucleotides, leading to purine nucleotide deficiencies in rat brains. Here, we determined the effect of exogenous purine nucleotide administration on purine nucleotide metabolism in the brains of heroin-dependent rats. Heroin was administrated in increasing doses for 9 consecutive days to induce addiction, and the biochemical changes associated with heroin and purine nucleotide administration were compared among the treated groups. HPLC was performed to detect the absolute concentrations of purine nucleotides in the rat brain cortices. The enzymatic activities of adenosine deaminase (ADA) and xanthine oxidase (XO) in the treated rat cortices were analyzed, and qRT-PCR was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Purine nucleotide/quantitative analysis; Purine nucleotide/effects/brain rats; Heroin analysis; Adenosine deaminase analysis; Xanthine oxidase analysis. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400787 Registros recuperados: 3 Primeira ... 1 ... Última

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