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	Provedor de dados BJID (1) Autor Chen,Tong-Xin (1) Jin,Ying-Ying (1) Li,Yu-Feng (1) Wang,Juan-Juan (1) Wang,Xi (1) Palavra-chave Apoptosis (1) Dendritic cells (1) Epstein-Barr virus infections (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2012 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Effects of Epstein-Barr virus on the development of dendritic cells derived from cord blood monocytes: an essential role for apoptosis BJID Wang,Juan-Juan; Li,Yu-Feng; Jin,Ying-Ying; Wang,Xi; Chen,Tong-Xin. OBJECTIVE: Epstein-Barr virus (EBV) is a ubiquitous human γ-herpes virus, which can adapt and evade host immune defense. Dendritic cells (DCs) play a pivotal role in the initiation and maintenance of immune responses. This study investigated the effects of EBV on cord blood monocytes derived DCs (CBDC). METHODS: Monocytes were isolated from cord blood and cultured in medium containing recombinant IL-4 and GM-CSF to induce DCs development. B95-8 supernatant was added in monocytes culture medium for EBV infection at day 0. Phenotypic characterization of DCs, apoptotic cells, and mitochondrial membrane potential (MMP) were detected by flow cytometry. The morphology was observed by Hoechst 33258 staining and TUNEL staining, the expression of X-linked inhibitor... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dendritic cells; Apoptosis; Epstein-Barr virus infections. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100004 Registros recuperados: 1 Primeira ... 1 ... Última

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