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	Provedor de dados 56 (3) Autor Cherdshewasart,W. (3) Boonchird,C. (1) Chulasiri,M. (1) Ketsuwan,A. (1) Mahapanichkul,T. (1) Malaivijitnond,S. (1) Pulcharoen,K. (1) Sutjit,W. (1) Taya,K. (1) Watanabe,G. (1) Mais... Palavra-chave Phytoestrogen (2) Pueraria mirifica (2) Antimutagenic test (1) Butea superba (1) Estrogen receptor α (ERα) (1) Estrogen receptor β (ERβ) (1) Isoflavonoid (1) Luteinizing hormone (1) Micronucleus test (1) Mutagenic test (1) Pueraria lobata (1) Seminal vesicle (1) Testis (1) Testosterone propionate (1) YES assay (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2010 (2) 2009 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última The mutagenic and antimutagenic effects of the traditional phytoestrogen-rich herbs, Pueraria mirifica and Pueraria lobata 56 Cherdshewasart,W.; Sutjit,W.; Pulcharoen,K.; Chulasiri,M.. Pueraria mirifica is a Thai phytoestrogen-rich herb traditionally used for the treatment of menopausal symptoms. Pueraria lobata is also a phytoestrogen-rich herb traditionally used in Japan, Korea and China for the treatment of hypertension and alcoholism. We evaluated the mutagenic and antimutagenic activity of the two plant extracts using the Ames test preincubation method plus or minus the rat liver mixture S9 for metabolic activation using Salmonella typhimurium strains TA98 and TA100 as indicator strains. The cytotoxicity of the two extracts to the two S. typhimurium indicators was evaluated before the mutagenic and antimutagenic tests. Both extracts at a final concentration of 2.5, 5, 10, or 20 mg/plate exhibited only mild cytotoxic effects. The... Tipo: Info:eu-repo/semantics/article Palavras-chave: Phytoestrogen; Pueraria mirifica; Pueraria lobata; Mutagenic test; Antimutagenic test; Micronucleus test. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000900008 Differential binding with ERα and ERβ of the phytoestrogen-rich plant Pueraria mirifica 56 Boonchird,C.; Mahapanichkul,T.; Cherdshewasart,W.. Variations in the estrogenic activity of the phytoestrogen-rich plant, Pueraria mirifica, were determined with yeast estrogen screen (YES) consisting of human estrogen receptors (hER) hERα and hERβ and human transcriptional intermediary factor 2 (hTIF2) or human steroid receptor coactivator 1 (hSRC1), respectively, together with the β-galactosidase expression cassette. Relative estrogenic potency was expressed by determining the β-galactosidase activity (EC50) of the tuber extracts in relation to 17β-estradiol. Twenty-four and 22 of the plant tuber ethanolic extracts interacted with hERα and hERβ, respectively, with a higher relative estrogenic potency with hERβ than with hERα. Antiestrogenic activity of the plant extracts was also determined by incubation... Tipo: Info:eu-repo/semantics/article Palavras-chave: YES assay; Estrogen receptor α (ERα); Estrogen receptor β (ERβ); Phytoestrogen; Isoflavonoid; Pueraria mirifica. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000200010 Luteinizing hormone reduction by the male potency herb, Butea superba Roxb. 56 Malaivijitnond,S.; Ketsuwan,A.; Watanabe,G.; Taya,K.; Cherdshewasart,W.. To determine if Butea superba Roxb., a traditional Thai male potency herb, has androgenic activity in 60-day-old male Wistar rats, we measured its effects on the pituitary-testicular axis and sex organs. Intact and orchidectomized adult male rats were subdivided into five groups (10 rats/group): distilled water, Butea superba (BS)-10, BS-50, BS-250, and testosterone propionate (TP). They received 0, 10, 50, and 250 mg·kg body weight-1·day-1 BS in distilled water by gavage and 6 mg·kg body weight-1·day-1 TP sc, respectively, during the 30-day treatment period. Blood was collected every 15 days and luteinizing hormone (LH), follicle-stimulating hormone (FSH) and testosterone were measured. Changes of weight and histological appearance of sex organs were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Butea superba; Testosterone propionate; Testis; Seminal vesicle; Luteinizing hormone. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000900006 Registros recuperados: 3 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco