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| Ávila,Renata Eliane de; Carmo,Ricardo Andrade; Farah,Kátia de Paula; Teixeira,Antônio Lúcio; Coimbra,Lucas Viana; Antunes,Carlos MaurÃcio de Figueiredo; Lambertucci,José Roberto. |
| BACKGROUND: This study evaluated the role of HA as a marker of liver fibrosis in patients with hepatitis C on haemodialysis. METHODS: This is a cross-sectional study in which 52 patients were divided into two groups: Group 1: patients with hepatitis C and end-stage renal disease (ESRD) undergoing haemodialysis (n = 23); and Group 2: patients with hepatitis C without ESRD (n = 29). Plasma levels of HA were associated with histological data of the samples obtained by liver biopsy and classified by METAVIR group scoring system. RESULTS: Higher plasma levels were significantly correlated to significant liver fibrosis (METAVIR > F2). In Group 1, the HA cutoff to discriminate significant fibrosis was 984.8 ng/mL, with accuracy, sensitivity and specificity of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Liver fibrosis; Hyaluronic acid; End-stage renal disease; Haemodialysis; Hepatitis C. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000400004 |
