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Antimicrobial activity of the Nisin Z producer Lactococcus lactis subsp. lactis Lc08 against Listeria monocytogenes in skim milk Arq. Bras. Med. Vet. Zootec.
Perin,L.M.; Miranda,R.O.; Camargo,A.C.; Colombo,M.; Carvalho,A.F.; Nero,L.A..
The presented study aimed to verify the effect of different pH values, enzyme solutions and heat treatments on the antimicrobial activity of the bacteriocinogenic strain Lactococcus lactis subsp. lactis Lc08 and to test their antimicrobial activity against Listeria monocytogenes in reconstituted skim milk at refrigeration temperatures. This strain was previously described as a nisin Z producer and capable of inhibiting L. monocytogenes growth in in vitro tests. The antimicrobial activity of the bacteriocin cell-free supernatant of Lc08 was sensitive to enzyme treatments (except papain). The pH values and heating (65ºC for 30min, 75ºC for 15s) had no apparent effect on the antimicrobial activity of the bacteriocin produced by Lc08. Only treatment at...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nisin Z; Milk; Antagonistic activity; Lactococcus lactis subsp. lactis; Listeria monocytogenes.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000500037
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VPA/PLGA microfibers produced by coaxial electrospinning for the treatment of central nervous system injury BJMBR
Reis,K.P.; Sperling,L.E.; Teixeira,C.; Sommer,L.; Colombo,M.; Koester,L.S.; Pranke,P..
The central nervous system shows limited regenerative capacity after injury. Spinal cord injury (SCI) is a devastating traumatic injury resulting in loss of sensory, motor, and autonomic function distal from the level of injury. An appropriate combination of biomaterials and bioactive substances is currently thought to be a promising approach to treat this condition. Systemic administration of valproic acid (VPA) has been previously shown to promote functional recovery in animal models of SCI. In this study, VPA was encapsulated in poly(lactic-co-glycolic acid) (PLGA) microfibers by the coaxial electrospinning technique. Fibers showed continuous and cylindrical morphology, randomly oriented fibers, and compatible morphological and mechanical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coaxial electrospinning; VPA; Spinal cord injury.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000400606
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