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| Lopes,H.F.; Consolim-Colombo,F.M.; Barreto-Filho,J.A.S.; Riccio,G.M.G.; Negrão,C.E.; Krieger,E.M.. |
| Malignant hypertension seems to be the consequence of very high blood pressure. Furthermore, an increase in sympathetic and renin-angiotensin system activity is considered to be the main mechanisms producing malignant hypertension. In the present study, 10 offspring of malignant hypertensive (OMH) parents (age 28 ± 5 years, 7 males, 3 females, 2 white and 8 non-white) and 10 offspring of normotensive (ONT) parents (age 28 ± 6 years, 2 males, 8 females, 3 white and 7 non-white) were evaluated. The OMH group had significantly higher (P < 0.05) casual blood pressure (125 ± 10/81 ± 5 mmHg) compared with ONT (99 ± 13/67 ± 5 mmHg). The increase in blood pressure was greater in OMH (Δ SBP = 17 ± 2 vs Δ SBP = 9 ± 1 mmHg in ONT) during cold pressor testing, but... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Malignant hypertension; Offspring of malignant hypertensive parents; Sympathetic activity; Microneurography. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001000003 |
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| Silva,G.J.J.; Ushizima,M.R.; Lessa,P.S.; Cardoso,L.; Drager,L.F.; Atala,M.M.; Consolim-Colombo,F.M.; Lopes,H.F.; Cestari,I.A.; Krieger,J.E.; Krieger,E.M.. |
| The autonomic nervous system plays an important role in physiological and pathological conditions, and has been extensively evaluated by parametric and non-parametric spectral analysis. To compare the results obtained with fast Fourier transform (FFT) and the autoregressive (AR) method, we performed a comprehensive comparative study using data from humans and rats during pharmacological blockade (in rats), a postural test (in humans), and in the hypertensive state (in both humans and rats). Although postural hypotension in humans induced an increase in normalized low-frequency (LFnu) of systolic blood pressure, the increase in the ratio was detected only by AR. In rats, AR and FFT analysis did not agree for LFnu and high frequency (HFnu) under basal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fast Fourier transform; Autoregressive model; Hypertension; SHR; Pharmacological blockade; Tilt test. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000400012 |
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| Lopes,H.F.; Silva,H.B.; Consolim-Colombo,F.M.; Barreto Filho,J.A.S.; Riccio,G.M.G.; Giorgi,D.M.A.; Krieger,E.M.. |
| Although a slightly elevated office blood pressure (BP) has been reported in several studies, little is known about the prolonged resting blood pressure, heart rate (HR) and baroreflex sensitivity (BRS) of prehypertensive subjects with a family history of hypertension. Office blood pressure, prolonged resting (1 h) BP and HR were measured in 25 young normotensives with a positive family history of hypertension (FH+) and 25 young normotensives with a negative family history of hypertension (FH-), matched for age, sex, and body mass index. After BP and HR measurements, blood samples were collected for the determination of norepinephrine, plasma renin activity and aldosterone levels, and baroreflex sensitivity was then tested. Casual BP, prolonged resting BP... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Heart rate; Blood pressure; Baroreflex sensitivity; Family history of hypertension. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000100007 |
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