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Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging BJPS
Cefali,Letícia Caramori; Souza-Moreira,Tatiana Maria; Corrêa,Marcos Antônio; Salgado,Hérida Regina Nunes; Isaac,Vera Lucia Borges.
Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Carotenoid/antioxidant activity; Lycopene/emulsion form/cytotoxicity; Lycopene/emulsion form/permeation; Lycopene/emulsion form/rheology; Lycopene/emulsion form/thermal analyses; Phytocosmetics; Skin aging/treatment.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300579
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Relationship between composition and organizational levels of nanostructured systems formed by Oleth 10 and PPG-5-Ceteth-20 for potential drug delivery BJPS
Rissi,Nathalia Cristina; Guglielmi,Danila Aparecida Scatolin; Corrêa,Marcos Antônio; Chiavacci,Leila Aparecida.
In this paper, nanostructured systems were developed, with the aid of ternary phase diagrams, from two surfactants, of differing degrees of lipophilicity (PPG-5-Ceteth-20 and the Oleth 10) and two oil phases (oleic acid and isopropyl myristate). It was observed that there were differences between the four resulting phase diagrams in the physical properties of the systems they represent. Thus, due to the capacity of Oleth 10 (as surfactant) and oleic acid (as the oil phase) to reduce interfacial tension, large regions of translucent systems were seen on the diagrams produced by them. By polarized light microscopy, it was possible to identify the isotropic and anisotropic properties of these systems, which were confirmed by small-angle X-ray scattering...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ternary phase diagrams; Nanostructured systems; Small-angle X-ray scattering/profiles; Drugs/delivery systems.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300653
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