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| Damasco,Andreia Paredes; Costa,Thaina Miranda da; Morgado,Priscylla Guimarães Migueres; Guimarães,Lorrayne Cardoso; Cavalcante,Fernanda Sampaio; Nouér,Simone Aranha; Santos,Kátia Regina Netto dos. |
| ABSTRACT Introduction: This study aimed to characterize Staphylococcus aureus isolates from bloodstream infections in patients attending a teaching hospital, between 2011 and 2015. Methods: The minimum inhibitory concentration for daptomycin, linezolid, oxacillin, teicoplanin, vancomycin, and trimethoprim/sulfamethoxazole was accessed by broth microdilution. SCCmec type and clonal profile were determined by molecular tests. Vancomycin heteroresistance was evaluated using screening tests and by population analysis profile/area under the curve. Results: Among 200 S. aureus isolates, 55 (27.5%) were MRSA, carrying SCCmec II (45.5%) or IV (54.5%). The most frequent MRSA lineages were USA100 (ST5-II) (45.5%) and USA800 (ST5-IV) (30.9%). Six isolates were... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Bloodstream infection; S. aureus; Vancomycin; Daptomycin. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000200139 |
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| Chamon,Raiane Cardoso; Ribeiro,Sthefanie da Silva; Costa,Thaina Miranda da; Nouér,Simone Aranha; Santos,Katia Regina Netto dos. |
| Abstract Staphylococcus aureus is an important cause of bloodstream infections. Therefore, the main purpose of this work was to characterize a collection of 139 S. aureus isolates from bloodstream infections in two public hospitals in relation to their antimicrobial susceptibility profile, staphylococcal cassette chromosome mec types, and clonal relationship. Methicillin resistance and resistance to other 12 agents were accessed by the disk diffusion test. Minimum inhibitory concentration to mupirocin was also determined. The SCCmec types were accessed by multiplex PCR, and the clonal relationship was determined by pulsed field gel electrophoresis method and restriction modification system characterization. Besides, multilocus sequence typing was performed... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Staphylococcus aureus; Bloodstream infections; USA100; Mupirocin resistance. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000200185 |
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