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| Santos,Fernanda M. dos; Souza,Maria Gorete de; Crotti,Antônio E. Miller; Martins,Carlos H. G.; Ambrósio,Sérgio R.; Veneziani,Rodrigo C. S.; Silva,Márcio L. Andrade e; Cunha,Wilson R.. |
| This work describes the phytochemical study of the extracts from aerial parts of Tibouchina candolleana as well as the evaluation of the antimicrobial activity of extracts, isolated compounds, and semi-synthetic derivatives of ursolic acid against endodontic bacteria. HRGC analysis of the n-hexane extract of T. candolleana allowed identification of b-amyrin, a-amyrin, and b-sitosterol as major constituents. The triterpenes ursolic acid and oleanolic acid were isolated from the methylene chloride extract and identified. In addition, the flavonoids luteolin and genistein were isolated from the ethanol extract and identified. The antimicrobial activity was investigated via determination of the minimum inhibitory concentration (MIC) using the broth... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tibouchina candolleana; Ursolic acid; Antimicrobial activity. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200045 |
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