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| Leandro,Luís F.; Mendes,Carlos A.; Casemiro,Luciana A.; Vinholis,Adriana H.C.; Cunha,Wilson R.; Almeida,Rosana de; Martins,Carlos H.G.. |
| In this work, we used the Minimum Inhibitory Concentration (MIC) technique to evaluate the antibacterial potential of the apitoxin produced by Apis mellifera bees against the causative agents of tooth decay. Apitoxin was assayed in naturaand in the commercially available form. The antibacterial actions of the main components of this apitoxin, phospholipase A2, and melittin were also assessed, alone and in combination. The following bacteria were tested: Streptococcus salivarius, S. sobrinus, S. mutans, S. mitis, S. sanguinis, Lactobacillus casei, and Enterococcus faecalis. The MIC results obtained for the commercially available apitoxin and for the apitoxin in natura were close and lay between 20 and 40µg / mL, which indicated good antibacterial activity.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial activity; Apitoxin; Melittin; Phospholipase A2; Tooth decay; Oral pathogens. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100147 |
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| Santos,Fernanda M. dos; Souza,Maria Gorete de; Crotti,Antônio E. Miller; Martins,Carlos H. G.; Ambrósio,Sérgio R.; Veneziani,Rodrigo C. S.; Silva,Márcio L. Andrade e; Cunha,Wilson R.. |
| This work describes the phytochemical study of the extracts from aerial parts of Tibouchina candolleana as well as the evaluation of the antimicrobial activity of extracts, isolated compounds, and semi-synthetic derivatives of ursolic acid against endodontic bacteria. HRGC analysis of the n-hexane extract of T. candolleana allowed identification of b-amyrin, a-amyrin, and b-sitosterol as major constituents. The triterpenes ursolic acid and oleanolic acid were isolated from the methylene chloride extract and identified. In addition, the flavonoids luteolin and genistein were isolated from the ethanol extract and identified. The antimicrobial activity was investigated via determination of the minimum inhibitory concentration (MIC) using the broth... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tibouchina candolleana; Ursolic acid; Antimicrobial activity. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200045 |
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