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Peritoneal and serum interleukin-18 levels are not increased in women with minimum or mild endometriosis BJMBR
Glitz,C.; Souza,C.A.; Rodini,G.P.; Genro,V.; Bilibio,J.P.; Senger,M.; Cunha-Filho,J.S..
Interleukin-18 (IL-18) is a cytokine that belongs to the IL-1 family. Endometriosis is strongly associated with sub-fertility, and affects about 15% of women of reproductive age. IL-18 may favor the progression of endometriosis. The objective of the present study was to determine the concentration of IL-18 in the serum and peritoneal fluid of infertile women with endometriosis. Forty infertile and 25 fertile women were screened in a teaching hospital. Thirty-four infertile patients with minimal or mild endometriosis and 22 fertile controls were enrolled in the study. The primary outcome was the estimate of IL-18 levels and the secondary outcome was the correlation between serum and peritoneal levels of IL-18. There were no differences between the two...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Endometriosis; IL-18; Peritoneal fluid; Infertility.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100007
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