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| ALVES,JODEL S.; SILVA,FERNANDA R. DA; SILVA,GABRIELI F. DA; SALVADOR,MIRIAN; KVITKO,KÁTIA; ROHR,PAULA; SANTOS,CARLA E.I. DOS; DIAS,JOHNNY F.; HENRIQUES,JOÃO A.P.; SILVA,JULIANA DA. |
| ABSTRACT Agricultural workers involved in the harvest of tobacco crops are regularly exposed to large quantities of pesticides. In order to determine how this exposure to pesticides induces genetic alterations in these workers, blood samples were obtained from 77 exposed individuals, as well as from 60 unexposed subjects. DNA damage was analyzed by the Comet assay and by the micronucleus (MN) test. The antioxidant profile was evaluated by activity of superoxide dismutase (SOD), and the polymorphism of gene PON1 was used as a susceptibility biomarker. The content of inorganic elements in the blood samples was determined by PIXE analysis. Our results demonstrated that the damage frequency, damage index, the MN frequency, and the SOD activity were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pesticides; Comet assay; Micronucleus test; Superoxide dismutase activity; PON1 gene. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100349 |
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| ZOCCHE,JAIRO J.; ROHR,PAULA; DAMIANI,ADRIANI P.; LEFFA,DANIELA D.; MARTINS,MIRIAM C.; ZOCCHE,CAROLINE M.; TEIXEIRA,KARINA O.; BORGES,GABRIELA D.; JESUS,MAIELLEN M. DE; SANTOS,CARLA E.I. DOS; DIAS,JOHNNY F.; ANDRADE,VANESSA M. DE. |
| ABSTRACT We assessed elemental composition of the liver in mice subjected to one-time or chronic consumption of the juice of vegetables cultivated in a vegetable garden built over deposits of coal waste. Lactuca sativa L. (lettuce), Beta vulgaris L. (beet), Brassica oleracea L. var. italica (broccoli) and Brassica oleracea L. var. acephala (kale) were collected from the coal-mining area and from a certified organic farm (control). Elemental composition was analyzed by particle-induced X-ray emission (PIXE) method. Concentrations of Mg, S, and Ca of mice subjected to one-time consumption of broccoli and concentrations of these same elements plus Si of mice receiving kale were higher in the coal-mining area. Concentrations of P, K, and Cu were increase after... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coal; Anthropogenic soil; Trace elements; Heavy metals; Plants; PIXE. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502383 |
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