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Genetic characterization of H5N2 influenza viruses isolated from wild birds in Japan suggests multiple reassortment OAK
Sultan, Serageldeen; Vuong Nghia Bui; Hill, Nichola J.; Hussein, Islam T. M.; Dai Quang Trinh; Inage, Kumiko; Hashizume, Taishi; Runstadler, Jonathan A.; Ogawa, Haruko; Imai, Kunitoshi.
Low-pathogenic avian influenza viruses (LPAIVs) of the H5 subtype can mutate to highly pathogenic forms, potentially destabilizing the poultry industry. Wild migratory birds are considered a natural reservoir of LPAIVs capable of dispersing both high- and low-pathogenic forms of the virus. Therefore, surveillance and characterization of AIV in wild birds are essential. Here, we report on the isolation and genetic characterization of 10 AIVs of the H5N2 subtype obtained through surveillance in Hokkaido, Japan, during 2009 and 2011. Full-genome sequencing revealed that the H5 and N2 genes of these isolates are all closely related to each other, belonging to the Eurasian avian-like lineage, but they are unrelated to H5 highly pathogenic strains of clade...
Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4568
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