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	Provedor de dados 56 (2) Autor Deakin,J.F.W. (2) Alves-Neto,W.C. (1) Del-Ben,C.M. (1) Graeff,F.G. (1) Guapo,V.G. (1) Guimarães,F.S. (1) Oliveira,R.M.W. (1) Mais... Palavra-chave Affective disorders (1) Emotion (1) Escitalopram (1) Facial expression (1) Hippocampus (1) Immunohistochemistry (1) Major depression (1) Neuronal nitric oxide synthase (1) Serotonin (1) Serotonin reuptake inhibitor (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2010 (1) 2008 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders 56 Oliveira,R.M.W.; Guimarães,F.S.; Deakin,J.F.W.. Hippocampal output is increased in affective disorders and is mediated by increased glutamatergic input via N-methyl-D-aspartate (NMDA) receptor and moderated by antidepressant treatment. Activation of NMDA receptors by glutamate evokes the release of nitric oxide (NO) by the activation of neuronal nitric oxide synthase (nNOS). The human hippocampus contains a high density of NMDA receptors and nNOS-expressing neurons suggesting the existence of an NMDA-NO transduction pathway which can be involved in the pathogenesis of affective disorders. We tested the hypothesis that nNOS expression is increased in the human hippocampus from affectively ill patients. Immunocytochemistry was used to demonstrate nNOS-expressing neurons in sections obtained from the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Affective disorders; Major depression; Neuronal nitric oxide synthase; Immunohistochemistry; Hippocampus. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000400012 Effect of escitalopram on the processing of emotional faces 56 Alves-Neto,W.C.; Guapo,V.G.; Graeff,F.G.; Deakin,J.F.W.; Del-Ben,C.M.. Serotonin has been implicated in the neurobiology of depressive and anxiety disorders, but little is known about its role in the modulation of basic emotional processing. The aim of this study was to determine the effect of the selective serotonin reuptake inhibitor, escitalopram, on the perception of facial emotional expressions. Twelve healthy male volunteers completed two experimental sessions each, in a randomized, balanced order, double-blind design. A single oral dose of escitalopram (10 mg) or placebo was administered 3 h before the task. Participants were presented to a task composed of six basic emotions (anger, disgust, fear, happiness, sadness, and surprise) that were morphed between neutral and each standard emotion in 10% steps. Escitalopram... Tipo: Info:eu-repo/semantics/other Palavras-chave: Serotonin; Escitalopram; Facial expression; Emotion; Serotonin reuptake inhibitor. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300010 Registros recuperados: 2 Primeira ... 1 ... Última

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