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Sensing Polymer/Paracetamol Interaction with an Independent Component Analysis-Based SERS-MIP Nanosensor ArchiMer
Decorbie, N.; Tijunelyte, I.; Gam-derouich, S.; Solard, J.; Lamouri, A.; Decorse, P.; Felidj, N.; Gauchotte-lindsay, C.; Rinnert, Emmanuel; Mangeney, C.; Lidgi-guigui, N..
In this article, we propose a new strategy to build a sensor for easy handling and rapid analysis on-site. Our sensor is based on the combination of surface-enhanced Raman spectroscopy (SERS) and molecularly imprinted polymers (MIPs). SERS provides a strong sensitivity for the detection of trace molecules while MIPs offer a highly selective and specific recognition platform. The research presented here focuses on the detection of the interaction between a robust ultra-thin layer of MIPs and of paracetamol, the targeted molecule. This drug is an environmental emerging pollutant, i.e., a molecule whose presence and significance have not yet been elucidated, which gives rise to health and environmental concerns. The results are a combined analysis of the SERS...
Tipo: Text Palavras-chave: Sensor; SERS; Molecularly imprinted polymers; Emerging pollutant; Paracetamol; Independent component analysis.
Ano: 2020 URL: https://archimer.ifremer.fr/doc/00628/73962/73386.pdf
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