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	Provedor de dados Biocell (1) Autor Brizuela,Nilda Y. (1) Demurtas,Silvia L. (1) Meirovich,Carlos I. (1) Montrull,Hilda L. (1) Spitale,Luis (1) Palavra-chave Chondrocytes (1) Collagenase (1) Osteoarthritis (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2005 (1) País Argentina (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Structure and secretory activity of cultured chondrocytes from patients with osteoarthritis Biocell Montrull,Hilda L.; Brizuela,Nilda Y.; Demurtas,Silvia L.; Spitale,Luis; Meirovich,Carlos I.. Cartilage samples were taken from OA patients in order to describe and quantify pro-inflammatory mediators. Samples were cultured under aseptic conditions in Dulbecco's modified Eagle medium at 37°C for 10 days. Control samples, taken from non-inflammatory cartilage, were cultured under the same conditions. The levels of NO-2 and NO-3 were measured in the supernatant using a spectrophotometric assay. The activity of MMP-1 was quantified by ELISA. The concentration of NO-x was 47.3 ± 4.1 µM in the OA cartilague and 10.7 ± 1.8 µM in the controls. The average MMP-1 activity was 3,650 ± 387 ng/ml in the OA cartilage and 2,150 ± 190 ng/ml in the control samples. These increased values of MMP-1 and NO-x observed in the OA cartilage suggest a higher catabolic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Osteoarthritis; Chondrocytes; Collagenase. Ano: 2005 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452005000200002 Registros recuperados: 1 Primeira ... 1 ... Última

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