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Health in early adulthood: the contribution of the 1978/79 Ribeirão Preto birth cohort BJMBR
Barbieri,M.A.; Bettiol,H.; Silva,A.A.M.; Cardoso,V.C.; Simões,V.M.F.; Gutierrez,M.R.P.; Castro,J.A.S.; Vianna,E.S.O.; Foss,M.C.; Dos Santos,J.E.; Queiroz,R.G.P..
The increase in non-communicable chronic diseases of adults is due to demographic changes and changes in the risk factors related to physical activity, smoking habits and nutrition. We describe the methodology for the evaluation of persons at 23/25 years of age of a cohort of individuals born in Ribeirão Preto in 1978/79. We present their socioeconomic characteristics and the profile of some risk factors for chronic diseases. A total of 2063 participants were evaluated by means of blood collection, standardized questionnaires, anthropometric and blood pressure measurements, and methacholine bronchoprovocation tests. The sexes were compared by the chi-square test, with alpha = 0.05. Obesity was similar among men and women (12.8 and 11.1%); overweight was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Non-communicable chronic diseases of adults; Metabolic syndrome; Obesity; Arterial hypertension Asthma; Dyslipidemia.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000800007
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Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians BJMBR
Souza,D.R.S.; De Godoy,M.R.; Hotta,J.; Tajara,E.H.; Brandão,A.C.; Pinheiro Júnior,S.; Tognola,W.A.; Dos Santos,J.E..
The genetic basis for dementias is complex. A common polymorphism in the apolipoprotein E (APOE) gene is considered to be the major risk factor in families with sporadic and late-onset Alzheimer's disease as well as in the general population. The distribution of alleles and genotypes of the APOE gene in late-onset Alzheimer's disease (N = 68), other late-life dementias (N = 39), and in cognitively normal controls (N = 58) was determined, as also was the risk for Alzheimer's disease associated with the epsilon4 allele. Peripheral blood samples were obtained from a total of 165 individuals living in Brazil aged 65-82 years. Genomic DNA was amplified by the polymerase chain reaction and the products were digested with HhaI restriction enzyme. APOE epsilon2...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Alzheimer's disease; Vascular dementia; Dementia; Apolipoprotein E; Aging; Genetic polymorphisms.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700013
Registros recuperados: 2
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