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Mega- change gene copies are produced by reverse transcription of precursor RNA with replaced introns. Nature Precedings
Drew Schwartz.
This report describes the presence of copy genes in plants where the sequence similarity to their parental genes is almost completely limited to limited to the exons. Evidence is presented that indicates that they arose via a novel processing of transcribed precursor RNA during which the introns are replaced rather than excised, followed by reverse transcription and incorporation into the chromosomes. Intron replacement may play an important role in evolution as it results in megagene changes.
Tipo: Manuscript Palavras-chave: Genetics & Genomics; Bioinformatics; Plant Biology; Evolutionary Biology.
Ano: 2009 URL: http://precedings.nature.com/documents/3834/version/1
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Altered copy gene function in plants following total intron replacement in precursor RNA Nature Precedings
Drew Schwartz.
Evidence is presented for two novel genetic mechanisms: total intron replacement in transcribedprecursor RNA by multiple short sequences and reverse transcription of the precursor RNA followedby incorporation into the genome as copy genes, some of which have acquired an altered function.
Tipo: Manuscript Palavras-chave: Genetics & Genomics; Molecular Cell Biology; Plant Biology; Evolutionary Biology.
Ano: 2010 URL: http://precedings.nature.com/documents/4307/version/1
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