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	Provedor de dados BJMBR (2) Autor Dronjak,S. (2) Gavrilovic,L. (2) Spasojevic,N. (1) Zivkovic,M. (1) Palavra-chave Adrenal glands (1) Catecholamines (1) Cold stress (1) Dopamine-β-hydroxylase (1) Heart auricles (1) Hippocampus (1) Hypothalamus (1) Immobilization stress (1) Phenylethanolamine N-methyltransferase gene expression (1) Tyrosine hydroxylase (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2009 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Effects of stress on catecholamine stores in central and peripheral tissues of long-term socially isolated rats BJMBR Dronjak,S.; Gavrilovic,L.. Both the peripheral sympatho-adrenomedullary and central catecholaminergic systems are activated by various psycho-social and physical stressors. Catecholamine stores in the hypothalamus, hippocampus, adrenal glands, and heart auricles of long-term socially isolated (21 days) and control 3-month-old male Wistar rats, as well as their response to immobilization of all 4 limbs and head fixed for 2 h and cold stress (4ºC, 2 h), were studied. A simultaneous single isotope radioenzymatic assay based on the conversion of catecholamines to the corresponding O-methylated derivatives by catechol-O-methyl-transferase in the presence of S-adenosyl-l-(³H-methyl)-methionine was used. The O-methylated derivatives were oxidized to ³H-vanilline and the radioactivity... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cold stress; Immobilization stress; Catecholamines; Hypothalamus; Hippocampus; Adrenal glands. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600011 Effect of immobilization stress on gene expression of catecholamine biosynthetic enzymes in heart auricles of socially isolated rats BJMBR Gavrilovic,L.; Spasojevic,N.; Zivkovic,M.; Dronjak,S.. Chronic stress is associated with the development of cardiovascular diseases. The sympathoneural system plays an important role in the regulation of cardiac function both in health and disease. In the present study, the changes in gene expression of the catecholamine biosynthetic enzymes tyrosine hydroxylase (TH), dopamine-β-hydroxylase (DBH) and phenylethanolamine N-methyltransferase (PNMT) and protein levels in the right and left heart auricles of naive control and long-term (12 weeks) socially isolated rats were investigated by Taqman RT-PCR and Western blot analysis. The response of these animals to additional immobilization stress (2 h) was also examined. Long-term social isolation produced a decrease in TH mRNA level in left auricles (about 70%)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heart auricles; Tyrosine hydroxylase; Phenylethanolamine N-methyltransferase gene expression; Dopamine-β-hydroxylase. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200011 Registros recuperados: 2 Primeira ... 1 ... Última

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