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Towards the optimization of botanical insecticides research: Aedes aegypti larvicidal natural products in French Guiana ArchiMer
Falkowski, Michaël; Jahn-oyac, Arnaud; Odonne, Guillaume; Flora, Claudiane; Estevez, Yannick; Touré, Seindé; Boulogne, Isabelle; Robinson, Jean-charles; Béreau, Didier; Petit, Philippe; Azam, Didier; Coke, Maïra; Issaly, Jean; Gaborit, Pascal; Stien, Didier; Eparvier, Véronique; Dusfour, Isabelle; Houël, Emeline.
Natural products have proven to be an immeasurable source of bioactive compounds. The exceptional biodiversity encountered in Amazonia, alongside a rich entomofauna and frequent interactions with various herbivores is the crucible of a promising chemodiversity. This prompted us to search for novel botanical insecticides in French Guiana. As this French overseas department faces severe issues linked to insects, notably the strong incidence of vector-borne infectious diseases, we decided to focus our research on products able to control the mosquito Aedes aegypti. We tested 452 extracts obtained from 85 species originating from 36 botanical families and collected in contrasted environments against an Aedes aegypti laboratory strain susceptible to all...
Tipo: Text Palavras-chave: Mosquito larvicides; Culicidae; Amazonian chemodiversity; Screening optimization; Quasi-Poisson generalized linear model; Chemical defense.
Ano: 2020 URL: https://archimer.ifremer.fr/doc/00514/62544/66894.pdf
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Resurgence risk for malaria, and the characterization of a recent outbreak in an Amazonian border area between French Guiana and Brazil ArchiMer
Mosnier, Emilie; Dusfour, Isabelle; Lacour, Guillaume; Saldanha, Raphael; Guidez, Amandine; Gomes, Margarete S.; Sanna, Alice; Epelboin, Yanouk; Restrepo, Johana; Davy, Damien; Demar, Magalie; Djossou, Félix; Douine, Maylis; Ardillon, Vanessa; Nacher, Mathieu; Musset, Lise; Roux, Emmanuel.
Background In 2017, inhabitants along the border between French Guiana and Brazil were affected by a malaria outbreak primarily due to Plasmodium vivax (Pv). While malaria cases have steadily declined between 2005 and 2016 in this Amazonian region, a resurgence was observed in 2017. Methods Two investigations were performed according to different spatial scales and information details: (1) a local study on the French Guiana border, which enabled a thorough investigation of malaria cases treated at a local village health center and the entomological circumstances in the most affected neighborhood, and (2) a regional and cross-border study, which enabled exploration of the regional spatiotemporal epidemic dynamic. Number and location of malaria cases were...
Tipo: Text Palavras-chave: Plasmodium vivax; Anopheles darlingi; French Guiana; Brazil; Transnational; Outbreak investigation; Indigenous south Americans; Malaria; Amazonia.
Ano: 2020 URL: https://archimer.ifremer.fr/doc/00632/74387/74081.pdf
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