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In vivo cytogenetic effects of multiple doses of dietary vegetable oils Genet. Mol. Biol.
Evangelista,Cristina Márcia Wolf; Antunes,Lusânia Maria Greggi; Bianchi,Maria de Lourdes Pires.
Polyphenols are potent antioxidants that are particularly abundant in the Mediterranean diet, with olive oil being the main fat source. A number of investigations have reported that phenolic compounds found in dietary oils are antioxidants and could provide protective effects by inhibiting DNA oxidative damage. However, few studies have been published on the biological activity of vegetable oils, including their possible mutagenic/antimutagenic effects. The objective of the current study was to investigate the cytogenetic effects of multiple doses of four vegetable oils in rat bone marrow cells and to examine the possible antimutagenic effects of these oils in chromosomal damage induced by the antitumor drug cisplatin. These oils are consumed by humans and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimutagenesis; Chromosomal aberrations; Vegetable oils; Wistar rats.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000400024
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