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SILVA,Nazaré Carneiro da; GONÇALVES,Suellen Ferreira; ARAÚJO,Luciana Silva de; KASPER,Aline Aparecida München; FONSECA,Amanda Luisa da; SARTORATTO,Adilson; CASTRO,Kelly Christina Ferreira; MORAES,Tânia Mara Pires; BARATTO,Leopoldo Clemente; VAROTTI,Fernando de Pilla; BARATA,Lauro Euclides Soares; MORAES,Waldiney Pires. |
ABSTRACT Malaria is a disease of global tropical distribution, being endemic in more than 90 countries and responsible for about 212 million cases worldwide in 2016. To date, the strategies used to eradicate this disease have been ineffective, without specific preventive measures such as vaccines. Currently, the existing therapeutic arsenal is limited and has become ineffective against the expansion of artemisinin-resistant Plasmodium, demonstrating the need for studies that would allow the development of new compounds against this disease. In this context, we studied the volatile oil obtained from rhizomes of Cyperus articulatus (VOCA), a plant species commonly found in the Amazon region and popularly used as a therapeutic alternative for the treatment of... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antiplasmodial; Artemisinin resistance; Chloroquine resistance; Malaria; Plasmodium falciparum; Plasmodium berghei. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672019000400334 |
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