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SERUM BIOCHEMICAL DETERMINATIONS OF PROPOLIS-TREATED RATS J. Venom. Anim. Toxins
SFORCIN,J.M.; FUNARI,S.R.C.; NOVELLI,E.L.B..
Ethanolic extracts of the bee glue, a resinous substance collected by honeybees called propolis, have been widely used in folk medicine since ancient times. Antibacterial, antifungal and thus antiseptic properties may represent the basis for the historical and present use of these extracts in dermatology, against inflammatory conditions and common colds. This work was carried out in order to verify possible biochemical alterations in some seric parameters of propolis-treated rats. It was shown that propolis possesses an antioxidant property and its administration did not affect either amylase and alanine transaminase activities or total protein concentration.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Serum; Biochemistry.
Ano: 1995 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000100005
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Immunomodulatory action of propolis on macrophage activation J. Venom. Anim. Toxins
ORSI,R.O.; FUNARI,S.R.C.; SOARES,A.M.V.C.; CALVI,S.A.; OLIVEIRA,S.L.; SFORCIN,J.M.; BANKOVA,V..
Propolis has been the subject of several recent studies, with the aim of elucidating its biological and pharmacological properties. Propolis has a well-known antimicrobial activity as well as antioxidant, antitumoral, antiinflammatory, and regenerative properties, but literature about its effects on the immune response is scarce. The goal of this work was to evaluate the propolis effect on macrophage activation by oxygen (H2O2) and nitrogen (NO) metabolite determination. Propolis was produced by africanized honeybees and hydroalcoholic solutions were prepared at different concentrations. Peritoneal macrophages were obtained from male BALB/c mice and culture cells were stimulated in vitro with propolis or interferon-gamma (IFN-gamma). In the in vivo assay,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Macrophages; Hydrogen peroxide; Nitric oxide.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200006
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IN VITRO ACTIVITY OF PROPOLIS AGAINST BACTERIAL AND YEAST PATHOGENS ISOLATED FROM HUMAN INFECTIONS J. Venom. Anim. Toxins
FERNANDES Jr.,A.; SUGIZAKI,M.F.; FOGO,M.L.; FUNARI,S.R.C.; LOPES,C.A.M..
The in vitro activity of propolis against 118 Staphylococcus aureus, 108 Escherichia coli, 60 Salmonella typhimurium, 50 Candida albicans, 23 Candida parapsilosis, 19 Candida tropicalis and 14 Candida guilliermondii isolated from human infections was studied by the agar dilution method. Among the bacteria, the Gram-negative were the least susceptible organisms showing minimal inhibitory concentration (MIC) for 90% of the strains tested ranging from 22.5 mg/ml - 10,2% V/V to 23.1 mg/ml - 10.5% V/V. The MIC's for Candida ranged from 0.80 mg/ml to > 11 mg/ml (0.40% V/V to > 5.0% V/V), the strains of C. parapsilosis being the least susceptible. The relative order of susceptibility among all isolates, was: S.aureus > C. tropicalis >...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Antimicrobial activity; Bacteria; Yeast pathogens; Candida sp.
Ano: 1995 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000200003
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POPULATION ANALYSIS OF SUSCEPTIBILITY TO PROPOLIS IN REFERENCE STRAINS OF Staphylococcus aureus AND Escherichia coli J. Venom. Anim. Toxins
FERNANDES Jr.,A.; LOPES,C. A. M.; SFORCIN,J. M.; FUNARI,S.R.C..
Susceptibility to several ethanolic extracts of propolis (EEP) concentrations was tested with the population analysis technique in reference strains of Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 35218). The results of these tests showed that all bacteria were killed by EEP concentrations approximately equal or higher (2.0% v/v- S. aureus; 10.0% v/v - E. coli) than the respective minimal inhibitory concentrations (MIC). Regarding the susceptibility to propolis, there was a homogeneity of data with the respective time kill curves showing a clear bactericidal effect during 6 to 9 h of exposition.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Population analysis; Susceptibility; Staphylococcus aureus; Escherichia coli.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200005
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