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The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir BJID
Schröeder,Regina; Michelon,Tatiana; Wurdig,João; Fagundes,Iara; Schio,Sadi; Sanchez,Leticia; Camargo,José J.; Sukkienik,Teresa C.; Pasqualotto,Alessandro C.; Neumann,Jorge.
The best strategy for control of cytomegalovirus (CMV) infection in lung transplant patients is still not determined. The aim of this study was to document the incidence of CMV infection in a cohort of lung transplant recipients under universal prophylaxis with intravenous ganciclovir. All patients received immunosuppressive regimens consisting of cyclosporine, azathioprine, and prednisone. Regardless of CMV serostatus, intravenous ganciclovir was prescribed for every patient in the first 3 months post-transplantation. CMV infection was defined as the detection of CMV pp65 in leukocytes. Eighty-two lung transplant patients were included over a 5-year period. The incidence of CMV infection in the first year post-transplantation was 68.3%, occurring after a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytomegalovirus; Antigenemia; Lung transplantation; Ganciclovir; Prophylaxis.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200008
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