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	Provedor de dados BJMBR (2) Autor Fan,Q.X. (2) Chen,X.Q. (1) Liu,G.J. (1) Lu,P. (1) Ma,Z.J. (1) Mei,J.Z. (1) Meng,X.R. (1) Wang,F. (1) Yue,D.L. (1) Zheng,Y.L. (1) Mais... Palavra-chave Esophageal adenocarcinoma (1) Esophageal cancer (1) Esophageal squamous-cell carcinoma (1) Gene ontology (1) Genetic variant (1) MiRNA expression network (1) Molecular marker (1) Pathway (1) Susceptibility (1) XRCC1 gene (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2014 (1) 2013 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Expression analysis of miRNA and target mRNAs in esophageal cancer BJMBR Meng,X.R.; Lu,P.; Mei,J.Z.; Liu,G.J.; Fan,Q.X.. We aimed to investigate miRNAs and related mRNAs through a network-based approach in order to learn the crucial role that they play in the biological processes of esophageal cancer. Esophageal squamous-cell carcinoma (ESCC) and adenocarcinoma (EAC)-related miRNA and gene expression data were downloaded from the Gene Expression Omnibus database, and differentially expressed miRNAs and genes were selected. Target genes of differentially expressed miRNAs were predicted and their regulatory networks were constructed. Differentially expressed miRNA analysis selected four miRNAs associated with EAC and ESCC, among which hsa-miR-21 and hsa-miR-202 were shared by both diseases. hsa-miR-202 was reported for the first time to be associated with esophageal cancer in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Esophageal adenocarcinoma; Esophageal squamous-cell carcinoma; MiRNA expression network; Pathway; Gene ontology. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000900811 Association between the c.910A>G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population BJMBR Chen,X.Q.; Wang,F.; Zheng,Y.L.; Fan,Q.X.; Yue,D.L.; Ma,Z.J.. Esophageal cancer (EC) is a common malignancy worldwide. The X-ray repair cross-complementing 1 gene (XRCC1) is one of the most important candidate genes for influencing susceptibility to EC. This study aimed to investigate the effect of XRCC1 genetic variants on susceptibility to EC. A total of 383 EC patients (males: 239, females: 144, mean age: 56.62) and 387 cancer-free controls (males: 251, females: 136, mean age: 58.23) were enrolled in this study. The c.910A>G genetic variant of theXRCC1 gene was determined by polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing methods. The allele and genotype frequencies indicated statistical differences between EC patients and cancer-free controls. The c.910A>G genetic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Esophageal cancer; XRCC1 gene; Genetic variant; Molecular marker; Susceptibility. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001201028 Registros recuperados: 2 Primeira ... 1 ... Última

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