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| Llanio, M. D.; Fernández, M. D.; Mata, A.; Cabrera, B.; Pérez, M.. |
| At present, there is a worldwide tendency to discover new drugs that provide an answer to treat different illnesses, many of them still without solution and others of difficult treatment. In the last two decades, diverse groups of scientists have concentrated on obtaining natural marine compounds, since they represent a source of new chemical structures. Marine pharmacology has focused its attention on some areas of pharmaceutical development with emphasis on cancer and on inflammatory illnesses. In this work we carry out the study of two extracts from sponges of the Cuban shelf as possible sources of anti-inflammatory and/or analgesic compounds. To achieve this objective the extracts were evaluated in the models of inhibition of phospholipase A2 of bee... |
| Tipo: Journal Contribution |
Palavras-chave: Sponges; Sponges; Http://aims.fao.org/aos/agrovoc/c_7321. |
| Ano: 2003 |
URL: http://hdl.handle.net/1834/3344 |
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| Llanio, M. D.; Fernández, M. D.; Mata, A.; Cabrera, B.; Valdés-Iglesias, O.; Díaz, C.; Cabranes, Y.. |
| Marine organisms represent a new source for the discovery of anti-inflammatory agents (Grace et al., 1994), mainly obtained starting from sponges, coelenterates and algae. A representative compound from algae, due to its great number of properties, is the epitaondiol that inhibits the phospholipase A2 and the formation and/or release of prostaglandins and leukotrienes. Taking into account these antecedents, we decided to evaluate extracts from four Rhodophyte algae species of the genera Laurencia, Acantophora and Gracilaria in the models of mouse ear oedema induced by croton oil, writhing induced by acetic acid in mouse, and the assay of the tiobarbituric acid (TBA). The objective was to detect antiinflammatory, analgesic and antioxidant properties of the... |
| Tipo: Journal Contribution |
Palavras-chave: Algae; Antioxidants; Algae; Antioxidants; Http://aims.fao.org/aos/agrovoc/c_258; Http://aims.fao.org/aos/agrovoc/c_511. |
| Ano: 2003 |
URL: http://hdl.handle.net/1834/3343 |
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