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Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients BJMBR
Donadi,E.A.; Voltarelli,J.C.; Paula-Santos,C.M.; Kimachi,T.; Ferraz,A.S..
A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty of Medicine of Ribeirão Preto, São Paulo, Brazil. HLA-A, -B, -DR and -DQ antigens were typed using a complement-dependent microlymphocytotoxicity assay. A control white population (N = 403) from the same geographical area was also typed for HLA antigens. Although the frequencies of HLA-A and -B antigens of patients were not statistically different from controls, the frequency of HLA-DR2 antigen observed in patients (65%) was significantly increased in relation to controls (26%; P<0.001). The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HLA antigens; Alport's syndrome; MHC; Immunogenetics.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000400010
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Exercise may cause myocardial ischemia at the anaerobic threshold in cardiac rehabilitation programs BJMBR
Fuchs,A.R.C.N.; Meneghelo,R.S.; Stefanini,E.; De Paola,A.V.; Smanio,P.E.P.; Mastrocolla,L.E.; Ferraz,A.S.; Buglia,S.; Piegas,L.S.; Carvalho,A.A.C..
Myocardial ischemia may occur during an exercise session in cardiac rehabilitation programs. However, it has not been established whether it is elicited when exercise prescription is based on heart rate corresponding to the anaerobic threshold as measured by cardiopulmonary exercise testing. Our objective was to determine the incidence of myocardial ischemia in cardiac rehabilitation programs according to myocardial perfusion SPECT in exercise programs based on the anaerobic threshold. Thirty-nine patients (35 men and 4 women) diagnosed with coronary artery disease by coronary angiography and stress technetium-99m-sestamibi gated SPECT associated with a baseline cardiopulmonary exercise test were assessed. Ages ranged from 45 to 75 years. A second...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Exercise test; Anaerobic threshold; Myocardial ischemia; Coronary artery disease; Technetium; 99mTc-sestamibi.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000300008
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