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	Provedor de dados BJPS (4) Autor Cruz,Letícia (4) Ferreira,Luana Mota (4) Chassot,Janaíne Micheli (2) Gomes,Felipe Pereira (2) Schaffazick,Scheila Rezende (2) Tasso,Leandro (2) Velasquez,Aline de Arce (2) Silva,Cristiane de Bona da (1) Mais... Palavra-chave Pullulan (2) Beclomethasone dipropionate/determination (1) Beclomethasone dipropionate/nanocapsules. (1) Biocompatible polymers (1) Excipients (1) High performance liquid chromatography/reverse phase/quantitative analysis (1) Microparticulate tablets (1) Microparticulated tablets/release profile (1) Nanocapsule/suspensions (1) Nanocapsules/diffusion technique (1) Nanoparticles. (1) Pullulan/polymeric stabilizer (1) Sodium alendronate (1) Sodium alendronate/controlled release/in vitro study (1) Sodium alendronate/oral administration (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2016 (1) 2015 (3) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Pullulan as a stabilizer agent of polymeric nanocapsules for drug delivery BJPS Chassot,Janaíne Micheli; Ferreira,Luana Mota; Gomes,Felipe Pereira; Silva,Cristiane de Bona da; Tasso,Leandro; Cruz,Letícia. ABSTRACT Polymeric stabilizers have received attention in the preparation of nanostructured systems due to their ability to enhance formulation stability. Considering this, the objective of this work was to prepare poly(ε-caprolactone) nanocapsules using the pullulan as a polymeric stabilizer. The nanocapsules were prepared using the interfacial deposition method of preformed polymers and they were characterized in terms of pH, average diameter, polydispersity index, zeta potential, beclomethasone dipropionate content, encapsulation efficiency, photostability and drug release profiles. The formulations showed physicochemical characteristics consistent with nanocarriers for drug delivery such as: average diameter lower than 270 nm, polydispersity indexes... Tipo: Info:eu-repo/semantics/article Palavras-chave: Pullulan; Nanocapsules/diffusion technique; Pullulan/polymeric stabilizer; Biocompatible polymers; Beclomethasone dipropionate/nanocapsules.. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400735 Stability-indicating RP-HPLC method for determination of beclomethasone dipropionate in nanocapsule suspensions BJPS Chassot,Janaíne Micheli; Ferreira,Luana Mota; Gomes,Felipe Pereira; Cruz,Letícia; Tasso,Leandro. abstract A simple stability-indicating RP-HPLC/UV method was validated for determination of beclomethasone dipropionate (BD) in nanocapsule suspensions. Chromatographic conditions consisted of a RP C18column (250 mm x 4.60 mm, 5 µm, 110 Å), using methanol and water (85:15 v/v) as mobile phase at 1.0 mL/min with UV detection at 254 nm. The calibration curve was found to be linear in the concentration range of 5.0-25.0 µg/mL with a correlation coefficient > 0.999. Precision was demonstrated by a relative standard deviation lower than 2.0%. Accuracy was assessed by the recovery test of BD from nanocapsules (98.03% to 100.35%). Specificity showed no interference from the components of nanocapsules or from the degradation products derived from acid, basic... Tipo: Info:eu-repo/semantics/article Palavras-chave: High performance liquid chromatography/reverse phase/quantitative analysis; Beclomethasone dipropionate/determination; Nanocapsule/suspensions; Nanoparticles.. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400803 Formulation of gastroresistant tablets containing sodium alendronate-loaded blend microparticles BJPS Ferreira,Luana Mota; Velasquez,Aline de Arce; Schaffazick,Scheila Rezende; Cruz,Letícia. Tipo: Info:eu-repo/semantics/article Palavras-chave: Microparticulated tablets/release profile; Sodium alendronate/oral administration; Sodium alendronate/controlled release/in vitro study. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000200323 Pullulan: an advantageous natural polysaccharide excipient to formulate tablets of alendronate-loaded microparticles BJPS Ferreira,Luana Mota; Velasquez,Aline de Arce; Schaffazick,Scheila Rezende; Cruz,Letícia. This work reports the preparation of tablets by direct compression of sodium alendronate-loaded microparticles, using pullulan as filler. The tableting properties of pullulan were compared with those of microcrystalline cellulose and lactose. Pullulan tablets showed low variations in average weight, thickness and drug content. Moreover, these tablets exhibited a higher hardness compared to the other excipients. In vitro release studies showed that only pullulan was capable to maintain gastroresistance and release properties of microparticles, due to its ability to protect particles against damage caused by compression force. Thus, pullulan was considered an advantageous excipient to prepare tableted microparticles. Tipo: Info:eu-repo/semantics/article Palavras-chave: Pullulan; Excipients; Microparticulate tablets; Sodium alendronate. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100027 Registros recuperados: 4 Primeira ... 1 ... Última

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