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	Provedor de dados Genet. Mol. Biol. (1) Autor Costa,S.O.P. (1) Ferreira,L.C.S. (1) Ferreira,R.C.C (1) Monteiro,A.C.M. (1) Padilla,G. (1) Palavra-chave Aminoglycosides (1) Antibiotic resistance (1) Escherichia coli K12 (1) Mutator strains (1) Spontaneous mutantion frequencies (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2003 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Environmental and genetic factors affecting mutability to aminoglycoside antibiotics among Escherichia coli K12 strains Genet. Mol. Biol. Monteiro,A.C.M.; Ferreira,R.C.C; Padilla,G.; Ferreira,L.C.S.; Costa,S.O.P.. Environmental and genetic factors affecting the in vitro spontaneous mutation frequencies to aminoglycoside resistance in Escherichia coli K12 were investigated. Spontaneous mutation frequencies to kanamycin resistance were at least 100 fold higher on modified Luria agar (L2) plates, when compared to results obtained in experiments carried out with Nutrient agar (NA) plates. In contrast to rifampincin, the increased mutability to kanamycin resistance could not be attributed to a mutator phenotype expressed by DNA repair defective strains. Kanamycin mutant selection windows and mutant preventive concentrations on L2 plates were at least fourfold higher than on NA plates, further demonstrating the role of growth medium composition on the mutability to... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antibiotic resistance; Aminoglycosides; Escherichia coli K12; Mutator strains; Spontaneous mutantion frequencies. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000200017 Registros recuperados: 1 Primeira ... 1 ... Última

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