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Seroprevalence of bactericidal antibodies against serogroup B and C Meningococci in a University Hospital BJMBR
Gioia,C.A.C.; Lemos,A.P.S.; Gorla,M.C.O.; Mendoza-Sassi,R.; Figueredo,B.S.; Ballester,T.; Von Groll,A.; Wedig,B.; Ethur,N.V.; Bragança,L.; Silva,P.E.A.; Milagres,L.G..
Meningococcus serogroup B (MenB), clonal complex 32 (cc 32), was the Brazilian epidemic strain of meningococcal disease (MD) in the 1990’s. Currently, meningococcus serogroup C (MenC), cc 103, is responsible for most of the cases of the disease in Brazil. The aim of this study was to investigate the seroprevalence of bactericidal antibody (SBA) against representative epidemic strains of MenC, (N753/00 strain, C:23:P1.22,14-6, cc103) and MenB, (Cu385/83 strain, B:4,7:P1.15,19, cc32) in students and employees of a university hospital in the State of Rio Grande do Sul (RS, Brazil). A second MenC strain (N79/96, C:2b:P1.5-2,10, cc 8) was used as a prototype strain of Rio de Janeiro’s outbreak that occurred in the 1990’s. Our previous study showed a 9% rate of...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Neisseria meningitidis; Bactericidal antibodies; Meningococcal carrier.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000500607
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