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da Cunha,Marcelo Rodrigues; Laraia,Isabela Ortiz; Franco,Guacira R; Miguel,Natalia N; Maciel,Ana A; dos Santos,Geovane Ribeiro; Isayama,Ricardo Noboro. |
Bone metabolism is influenced by different factors and muscle activity acts as a stimulator of bone plasticity. Conditions such as nerve injuries can compromise bone physiology due to muscle inactivity. Preview studies have shown that nerve damage reduces P substance and calcitonin gene-related peptides, also known as neuropeptides that may have a key role on bone healing. Therefore, this study evaluated the osseointegration of hydroxyapatite implants in tibial defects of rats submitted to unilateral sciatic nerve section. Twelve Wistar rats were divided into two groups (G1 and G2). In G1, the sciatic nerve was left intact and in G2 the left sciatic nerve was completely sectioned. An experimental tibial bone defect was then created in both groups and... |
Tipo: Journal article |
Palavras-chave: Hydroxyapatite; Sciatic nerve; Bone healing. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200033 |
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