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Vidal-dupiol, Jeremie; Dheilly, Nolwenn M.; Rondon, Rodolfo; Grunau, Christoph; Cosseau, Celine; Smith, Kristina M.; Freitag, Michael; Adjeroud, Mehdi; Mitta, Guillaume. |
Global change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. This has resulted in increased disease in natural plant and animal populations worldwide, including scleractinian corals. While the effects of temperature increase on immunity and pathogen virulence have been clearly identified, their interaction, synergy and relative weight during pathogenesis remain poorly documented. We investigated these phenomena in the interaction between the coral Pocillopora damicornis and the bacterium Vibrio coralliilyticus, for which the infection process is temperature-dependent. We developed an experimental model that enabled... |
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Ano: 2014 |
URL: http://archimer.ifremer.fr/doc/00221/33265/31738.pdf |
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Roquis, David; Lepesant, Julie M. J.; Picard, Marion A. L.; Freitag, Michael; Parrinello, Hugues; Groth, Marco; Emans, Remi; Cosseau, Celine; Grunau, Christoph. |
Background Chromatin structure can control gene expression and can define specific transcription states. For example, bivalent methylation of histone H3K4 and H3K27 is linked to poised transcription in vertebrate embryonic stem cells (ESC). It allows them to rapidly engage specific developmental pathways. We reasoned that non-vertebrate metazoans that encounter a similar developmental constraint (i.e. to quickly start development into a new phenotype) might use a similar system. Schistosomes are parasitic platyhelminthes that are characterized by passage through two hosts: a mollusk as intermediate host and humans or rodents as definitive host. During its development, the parasite undergoes drastic changes, most notable immediately after infection of the... |
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Ano: 2015 |
URL: https://archimer.ifremer.fr/doc/00615/72712/71721.pdf |
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