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Morphologic and biochemical changes in male rat lung after surgical and pharmacological castration BJMBR
Ojeda,M.S.; Gómez,N.N.; Gil,E.; Scardapane,L.; Gimenez,M.S..
The morphology of the rat lung was studied by light microscopy in different situations: after surgical and pharmacological castration and after administration of testosterone to the castrated rat to determine if the androgen is required to maintain the normal morphology of the lung. We also determined the effect of flutamide on the phospholipid composition of both the surfactant and microsomes of the lung. Rats were separated into five groups: I - control non-castrated rats, II - castrated rats sacrificed 21 days after castration, III - castrated rats that received testosterone daily from day 2 to day 21 after castration, IV - castrated rats that received testosterone from day 15 to day 21 after castration, and V - control rats injected with flutamide for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lung; Antiandrogens; Phospholipids; Flutamide; Lung morphology.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300004
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