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	Provedor de dados BABT (2) Autor Bazotte,Roberto Barbosa (2) Galletto,Ricardo (2) Ferreira,Edilene Bega (1) Oliveira,Arildo José Braz (1) Pagliarini e Silva,Sarah (1) Siqueira,Vera Lúcia Dias (1) Vardanega-Peicher,Márcia (1) Mais... Palavra-chave Asclepideceae (1) CAMP (1) Diabetes (1) Glucagon (1) Gymnema sylvestre (1) Hepatic glycogenolysis (1) Hepatic glycolysis (1) Herbal therapies (1) Isoproterenol (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2004 (1) 2003 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Absence of antidiabetic and hypolipidemic effect of Gymnema sylvestre in non-diabetic and alloxan-diabetic rats BABT Galletto,Ricardo; Siqueira,Vera Lúcia Dias; Ferreira,Edilene Bega; Oliveira,Arildo José Braz; Bazotte,Roberto Barbosa. In this study we investigated the antidiabetic and hypolipidemic potential of dried powdered leaves of Gymnema sylvestre (GS). The acute effect of GS administered by oral gavage on glucose blood level of and lipids in non-diabetic and alloxan-diabetic rats were investigated in the following conditions: a) after a balanced meal; b) after the ingestion of 1000 mg/kg amylose or 1000 mg/kg glucose; c) after the ingestion of a mixture of 12 mL/kg soybean oil + 1% cholesterol (SOC). In addition, the effect of the treatment with GS during two (sub-acute) or four weeks (chronic) on body weight, food and water ingestion, glucose blood level and lipids in non-diabetic and alloxan-diabetic rats were measured. The dose of GS utilized in the majority of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Gymnema sylvestre; Herbal therapies; Diabetes; Asclepideceae. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132004000400007 Comparative effect of glucagon and isoproterenol on hepatic glycogenolysis and glycolysis in isolated perfused liver BABT Vardanega-Peicher,Márcia; Galletto,Ricardo; Pagliarini e Silva,Sarah; Bazotte,Roberto Barbosa. The effect of glucagon and isoproterenol (beta-adrenergic agonist) on hepatic glycogenolysis and glycolysis in isolated perfused liver was compared. The levels of isoproterenol and glucagon which promoted the maximal activation of glycogenolysis were 20 muM and 1nM respectively. However, glucagon (1 nM) not only increased glycogenolysis but also inhibited glycolysis. Because adenosine-3'-5'-cyclic monophosphate (cAMP) is a common second messenger to glucagon and isoproterenol, the level of cAMP that simulates the effect of these substances were investigated. The concentration of cAMP that inhibited glycolysis was five times higher (15 muM) than that which stimulated glycogenolysis (3 muM). Similar inhibition of glycolysis was obtained with cAMP agonists... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatic glycolysis; Hepatic glycogenolysis; Glucagon; Isoproterenol; CAMP. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132003000400010 Registros recuperados: 2 Primeira ... 1 ... Última

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