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| Frischknecht, M.; Meuwissen, T.H.E.; Bapst, B.; Seefried, F.R.; Flury, C.; Garrick, D.; Signer-Hasler, H.; Stricker, C.; Consortium, Intergenomics; Bieber, Anna; Fries, R.; Russ, I.; Sölkner, J.; Bagnato, A.; Gredler-Grandl, B.. |
| The accuracy of genomic prediction determines response to selection. It has been hypothesized that accuracy of genomic breeding values can be increased by a higher density of variants. We used imputed whole-genome sequence data and various single nucleotide polymorphism (SNP) selection criteria to estimate genomic breeding values in Brown Swiss cattle. The extreme scenarios were 50K SNP chip data and whole-genome sequence data with intermediate scenarios using linkage disequilibrium-pruned whole-genome sequence variants, only variants predicted to be missense, or the top 50K variants from genome-wide association studies. We estimated genomic breeding values for 3 traits (somatic cell score, nonreturn rate in heifers, and stature) and found differences in... |
| Tipo: Journal paper |
Palavras-chave: Dairy cattle; Breeding and genetics. |
| Ano: 2018 |
URL: http://orgprints.org/35104/1/Frischknecht-etal-2018-JDairySci-Vol101-Issue2-p1292-1296.pdf |
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