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| Cordeiro,Yonara de Gouveia; Rochetti,Arina Lázaro; Souza,Vinicius Castro; Silva,Edson Roberto da; Scatolini,Antônio Márcio; Genovese,Maria Inés; Yasui,George Shigueki; Fukumasu,Heidge. |
| Abstract Lafoensia pacari A. St. Hill has been used in traditional medicine as an anti-ulcerogenic and anti-inflammatory. Although there is an ethnopharmacological indication for cancer treatment, only a few studies have demonstrated its possible anticancer activity. Thus, the aims of this study were: (1) to evaluate the antineoplastic effect of L. pacari ethanolic extract (LPE) in lung carcinoma cells, (2) to determine the mode of action of LPE and (3) to identify the substances present in LPE. Human and murine lung cancer cell lines were grown in vitro and treated with different concentrations of LPE. Cell cycle and caspase-3 activity assays were performed in order to verify the mode of action. LC-ESI-MS screening was performed to detect the compounds... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antineoplastic effect; Cell cytotoxicity; Medicinal plants; Procyanidins. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100302 |
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| Genovese,Maria Inés; Davila,Jorge; Lajolo,Franco M.. |
| Soy products produced in Ecuador, with a local developed and cultivated soybean variety (INIAP 306), were analysed for isoflavone content and profile. The products presented high total isoflavone contents, varying from 53 to 106 mg/100 g (wet basis, expressed as aglycones), the lowest content being for okara and the highest for the low fat soybean flour obtained by extrusion cooking of the seeds at the field moisture. Soy nuts showed the same content of isoflavones than the seeds, but with lower amounts of malonylglycosides and higher of the deesterified beta-glycosides. The malonylglycosides were the predominant form of the isoflavones in the flours, and the beta-glycosides in soymilk and textured soy protein. Genistein derivatives were the compounds... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ecuadorian soybean products; Isoflavone content; Isoflavone profile. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000600020 |
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