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	Provedor de dados BABT (3) BJM (1) Autor Giordano,Roberto de Campos (4) Giordano,Raquel de Lima Camargo (1) Iemma,Monica Rosas da Costa (1) Martins,Elizabeth Angélica Leme (1) Montano,Inti Doraci Cavalcanti (1) Novo-Mansur,Maria Teresa Marques (1) Nucci,Edson Romano (1) Pinto,Gilson Alexandre (1) Ribeiro,Marcelo Perencin de Arruda (1) Silva,Adilson José da (1) Sousa Júnior,Ruy de (1) Suarez,Carlos Alberto Galeano (1) Zangirolami,Teresa Cristina (1) Mais... Palavra-chave Antigen presentation (1) Bacillus megaterium (1) Bacterial vector (1) Cancer vaccine (1) Culture media (1) DNA vaccine (1) Enzymatic proteolysis (1) Fed-batch reactor optimization (1) Metabolic profile (1) On-line noisy signals filtering (1) Optimal control (1) PH control (1) Post-treatment noisy data (1) Synthesis of beta-lactam antibiotics (1) Vaccine delivery system (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2014 (1) 2012 (1) 2005 (2) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Variational calculus (optimal control) applied to the optimization of the enzymatic synthesis of ampicillin BABT Ribeiro,Marcelo Perencin de Arruda; Giordano,Roberto de Campos. In this work, optimal control techniques were used to optimize the feed of reactants during the enzymatic synthesis of ampicillin in a semi-batch reactor. Simulation results showed that a semi-batch integrated reactor (with product crystallization) might achieve 88% 6-APA (6-aminepenicillanic acid) conversion and 92% of PGME (phenylglycine methyl ester) yield, with a productivity between 3.5 and 5.5 mM min-1. Tipo: Info:eu-repo/semantics/article Palavras-chave: Synthesis of beta-lactam antibiotics; Fed-batch reactor optimization; Optimal control. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000400003 Comparison of performance of different algorithms in noisy signals filtering of process in enzymatic hydrolysis of cheese whey BABT Pinto,Gilson Alexandre; Sousa Júnior,Ruy de; Giordano,Roberto de Campos. This work presented the results of the implementation of an off-line smoothing algorithm in the monitoring system, for the partial hydrolysis of cheese whey proteins using enzymes, which used penalized least squares. Different algorithms for on-line signals filtering used by the control were also compared: artificial neural networks, moving average and smoothing algorithm. Tipo: Info:eu-repo/semantics/article Palavras-chave: Enzymatic proteolysis; PH control; Post-treatment noisy data; On-line noisy signals filtering. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000400019 Assessment of the metabolism of different strains of Bacillus megaterium BABT Suarez,Carlos Alberto Galeano; Montano,Inti Doraci Cavalcanti; Nucci,Edson Romano; Iemma,Monica Rosas da Costa; Giordano,Raquel de Lima Camargo; Giordano,Roberto de Campos. Bacillus megaterium is a promising host for expression of heterologous proteins. This paper reports the nutrient consumption patterns and production of metabolites for three different strains of B. megaterium, ATCC 14945, QMB 1551 and PV 361, which is QMB 1551 with seven constitutive plasmids deleted. 14 h cultivations in agitated flasks were run, for two different media: A (LB plus 10g/L glucose) and B (medium A, with the yeast extract replaced by tryptone). Strains PV361 and QMB 1551 showed higher maximum specific growth rates in medium B, reaching 0.42 h-1 and 0.48 h-1 respectively. The main by-products of the glucose overflow mechanism were acetate and lactate, for all three strains, which had preferential amino acids for substrate: Ala, Asp, Glu, Ser.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Metabolic profile; Bacillus megaterium; Culture media. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000400001 Live bacterial vaccine vectors: An overview BJM Silva,Adilson José da; Zangirolami,Teresa Cristina; Novo-Mansur,Maria Teresa Marques; Giordano,Roberto de Campos; Martins,Elizabeth Angélica Leme. Genetically attenuated microorganisms, pathogens, and some commensal bacteria can be engineered to deliver recombinant heterologous antigens to stimulate the host immune system, while still offering good levels of safety. A key feature of these live vectors is their capacity to stimulate mucosal as well as humoral and/or cellular systemic immunity. This enables the use of different forms of vaccination to prevent pathogen colonization of mucosal tissues, the front door for many infectious agents. Furthermore, delivery of DNA vaccines and immune system stimulatory molecules, such as cytokines, can be achieved using these special carriers, whose adjuvant properties and, sometimes, invasive capacities enhance the immune response. More recently, the unique... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacterial vector; Vaccine delivery system; DNA vaccine; Cancer vaccine; Antigen presentation. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400001 Registros recuperados: 4 Primeira ... 1 ... Última

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