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Survival benefits of interferon-based therapy in patients with recurrent hepatitis C after orthotopic liver transplantation BJMBR
Zanaga,L.P.; Vigani,A.G.; Angerami,R.N.; Giorgetti,A.; Escanhoela,C.A.F.; Ataíde,E.C.; Boin,I.F.S.F.; Stucchi,R.S.B..
Recurrent hepatitis C after orthotopic liver transplantation (OLT) is universal and can lead to graft failure and, consequently, reduced survival. Hepatitis C treatment can be used to prevent these detrimental outcomes. The aim of this study was to describe rates of hepatitis C recurrence and sustained virological response (SVR) to interferon-based treatment after OLT and its relationship to survival and progression of liver disease through retrospective analysis of medical records of 127 patients who underwent OLT due to cirrhosis or hepatocellular carcinoma secondary to chronic hepatitis C between January 2002 and December 2013. Fifty-six patients were diagnosed with recurrent disease, 42 started interferon-based therapy and 37 completed treatment....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; Liver transplantation; Sustained virological response; Recurrent hepatitis C; Transplantation outcomes.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000100701
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