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Histology and Renal Lipoperoxidation in Rats Exercised on a Treadmill and Submitted to Water Restriction International Journal of Morphology
Lorençoni,Roselene Modolo Regueiro; Pelai,Elisa Bizetti; Godoy,Moacir Fernandes; dos Santos,Alice Cristina Antonio; Miyoshi,Lívia Hissae; de Oliveira,Rebeca Nicolás Paronetto; Padovani,Carlos Roberto; Fregonesi,Cristina Elena Prado Teles; Camargo Filho,José Carlos Silva.
Physical effort stimulates an increase in oxygen consumption in tissues, generating toxic chemical species derived from oxygen (ROS), which are considered the initiators of the lipid peroxidation process (LPO), the major mechanism of cellular injury. As the essential mechanism for maintaining the electrolyte balance depends on an effective kidney function, oxidative stress in this organ can be a key factor in the development and persistence of hypertension. This study aimed to determine the kidney changes induced by a combination of fluid restriction and exercise in rats. The study consisted of 24 male Wistar rats of 90 days of age, divided into four groups, two of which were submitted to water restriction and exercise on a treadmill.Twenty-four hours...
Tipo: Journal article Palavras-chave: Morphology; Oxidative Stress; Kidney.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200039
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