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	Provedor de dados BJMBR (2) Autor Gonçales,N.S.L. (2) Corghi,D.B. (1) Fais,V.C. (1) Gonçales Jr.,F.L. (1) Gonçales Júnior,F.L. (1) Lazarini,M.S.K. (1) Marques,S.B.D. (1) Pavan,M.H.P. (1) Pereira,J.S.F. (1) Silva,C. (1) Mais... Palavra-chave Anti-HBc-positive patients (1) Chronic hepatitis C (1) HBV vaccination (1) HCV co-infection (1) HLA DR/DQ (1) HLA class II (1) HLA genotyping PCR (1) Hepatitis C virus (1) Interferon treatment (1) Occult HBV infection (1) Polymerase chain reaction (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2008 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Distribution of the human leukocyte antigen class II alleles in Brazilian patients with chronic hepatitis C virus infection BJMBR Corghi,D.B.; Gonçales,N.S.L.; Marques,S.B.D.; Gonçales Jr.,F.L.. Hepatitis C virus (HCV) infection is a global medical problem. The current standard of treatment consists of the combination of peginterferon plus ribavirin. This regimen eradicates HCV in 55% of cases. The immune response to HCV is an important determinant of disease evolution and can be influenced by various host factors. HLA class II may play an important role in immune response against HCV. The objective of the present study was to determine the distribution of HLA class II (DRB1 and DQB1) alleles, their association with chronic HCV infection and their response to interferon therapy. One hundred and two unrelated white Brazilian patients with chronic HCV infection, 52 responders (45 males and 7 females) and 50 non-responders (43 males and 7 females) to... Tipo: Info:eu-repo/semantics/article Palavras-chave: HLA class II; HLA DR/DQ; HLA genotyping PCR; Hepatitis C virus; Chronic hepatitis C; Interferon treatment. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001000009 HBV vaccination of HCV-infected patients with occult HBV infection and anti-HBc-positive blood donors BJMBR Pereira,J.S.F.; Gonçales,N.S.L.; Silva,C.; Lazarini,M.S.K.; Pavan,M.H.P.; Fais,V.C.; Gonçales Júnior,F.L.. Anti-HBc positivity is a frequent cause of donation rejection at blood banks. Hepatitis B virus (HBV) infection may also occur in HBsAg-negative patients, a situation denoted occult infection. Similarly, very low levels of HBV-DNA have also been found in the sera of patients with chronic hepatitis C virus (HCV) infection, even in the absence of serum HBsAg. Initially we searched for HBV-DNA in serum of 100 blood donors and 50 HCV-infected patients who were HBsAg negative/anti-HBc positive by nested-PCR and by an HBV monitor commercial test for HBV-DNA. Anti-HBs seroconversion rates were measured in 100 blood donors and in 22 patients with chronic HCV infection after HBV vaccination to determine if the HBV vaccination could eliminate an occult HBV infection... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polymerase chain reaction; Anti-HBc-positive patients; HCV co-infection; HBV vaccination; Occult HBV infection. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400013 Registros recuperados: 2 Primeira ... 1 ... Última

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