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	Provedor de dados BJPS (2) Autor Gratieri,Tais (2) Bentley,Maria Vitória Lopes Badra (1) Borgheti-Cardoso,Lívia Neves (1) Cunha-Filho,Marcilio (1) Gelfuso,Guilherme Martins (1) Kollross,Bianca (1) Vicentini,Fabiana Testa Moura de Carvalho (1) Mais... Palavra-chave Liquid crystalline systems/development (1) Nicotine/controlled transdermal delivery (1) Nicotine/transdermal patches (1) Ophthalmologic drug products (1) Registration/Brazil (1) Registration/United States (1) Skin irritation/control/in vitro study (1) Skin irritation/use of transdermal patches. (1) Vitamin E TPGS (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2016 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Liquid crystalline systems containing Vitamin E TPGS for the controlled transdermal nicotine delivery BJPS Borgheti-Cardoso,Lívia Neves; Vicentini,Fabiana Testa Moura de Carvalho; Gratieri,Tais; Bentley,Maria Vitória Lopes Badra. ABSTRACT Transdermal nicotine patches have been used in smoking cessation therapy, suggested for the treatment of skin disorders with eosinophilic infiltration and have been found to improve attention performance in patients with Alzheimer's disease and age-associated memory impairment. However, skin irritation with extended patch use is still a problem. The aim of this work was to develop a simple to prepare liquid crystalline system containing vitamin E TPGS that would be able to control nicotine delivery and reduce irritation and sensitization problems. The liquid crystalline phases were macroscopically characterized by visual analysis and examined microscopically under a polarized light microscope. Topical and transdermal delivery of nicotine were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nicotine/transdermal patches; Nicotine/controlled transdermal delivery; Liquid crystalline systems/development; Vitamin E TPGS; Skin irritation/control/in vitro study; Skin irritation/use of transdermal patches.. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000100021 Topical ophthalmic antimicrobials: unfulfilled demands and possibility of new investments in Brazil and in the United States BJPS Kollross,Bianca; Gelfuso,Guilherme Martins; Cunha-Filho,Marcilio; Gratieri,Tais. In general, topical ophthalmic drug products, especially those used for treating infections, present low effectiveness because of various reasons, from unfavorable drug physicochemical properties to physiological protective mechanisms of the eye. The fact is such group of products holds room for improvement, which could mean the development of better drugs or dosage forms. To achieve this, the knowledge of market composition is essential. The present work studied and compared the antimicrobial ophthalmic markets of Brazil and of the United States (US). Official databank of Brazilian Health Regulatory Agency and of US Food and Drug Administration were assessed for registered antimicrobial topical ophthalmic drug products. Brazilian market has registered... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ophthalmologic drug products; Registration/Brazil; Registration/United States. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100573 Registros recuperados: 2 Primeira ... 1 ... Última

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