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| Vilos,Cristian; Gutiérrez,Marlen; Escobar,Roberto A; Morales,Francisco; Denardin,Juliano C; Velasquez,Luis; Altbir,Dora. |
| Background: The progress in material science and the recent advances in biodegradable/biocompatible polymers and magnetic iron oxide nanoparticles have led to develop innovative diagnostic and therapeutic strategies for diseases based on multifunctional nanoparticles, which include contrast medium for magnetic resonance imaging, agent for hyperthermia and nanocarriers for targeted drug delivery. The aim of this work is to synthesize and characterize superparamagnetic iron oxide (magnetite), and to encapsulate them into poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanoparticles for biomedical applications. Results: The magnetite nanoparticles were confirmed by X-ray diffraction and exhibited a size of 22.3 ± 8.8 nm measured by transmission electron... |
| Tipo: Journal article |
Palavras-chave: Hyperthermia; Magnetic resonance image; Magnetite; PHBV; Polymeric nanoparticles. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000500008 |
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