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	Provedor de dados Biol. Res. (1) Autor HIROI,RYOKO (1) LAING,ROBYN (1) LASIENE,JÚRATE (1) OLAVARRÍA,JAIME F (1) Palavra-chave Corpus callosum (1) Interhemispheric commissure (1) Map (1) NMDAR (1) Striate cortex (1) Tipo do documento Journal article (1) Ano 2008 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Topography and axon arbor architecture in the visual callosal pathway: effects of deafferentation and blockade of TV-methyl-D-aspartate receptors Biol. Res. OLAVARRÍA,JAIME F; LAING,ROBYN; HIROI,RYOKO; LASIENE,JÚRATE. Visual callosal fibers link cortical loci in opposite hemispheres that represent the same visual field but whose locations are not mirror-symmetric with respect to the brain midline. Presence of the eyes from postnatal day 4 (P4) to P6 is required for this map to be specified. We tested the hypothesis that specification of the callosal map requires the activation of A'-methyl-D-aspartate receptors (NMDARs). Our results show that blockade of NMDARs with MK-801 during this critical period did not induce obvious abnormalities in callosal connectivity patterns, suggesting that retinal influences do not opérate through NMDAR-mediated processes to specify normal callosal topography. In contrast, we found that interfering with NMDAR function either through... Tipo: Journal article Palavras-chave: Corpus callosum; Interhemispheric commissure; Map; NMDAR; Striate cortex. Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000400007 Registros recuperados: 1 Primeira ... 1 ... Última

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