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| Lu, X.-L.; Najafzadeh, M.J.; Dolatabadi, S.; Ran, Y.-P.; Shen, Y.-N.; Li, C.-Y.; Xi, L.-Y.; Hao, F.; Zhang, Q.-Q.; Li, R.-Y.; Hu, Z.-M.; Lu, G.-X.; Wang, J.-J.; Drogari-Apiranthitou, M.; Klaassen, C.; Meis, J.F.; Hagen, F.; Liu, W.-D.; Hoog, G.S. de. |
| Mucormycosis usually presents as a progressive infection with significant angio-invasion. Mucormycosis due to Mucor irregularis (formerly Rhizomucor variabilis var. variabilis), however, is exceptional in causing chronic cutaneous infection in immunocompetent humans, ultimately leading to severe morbidity if left untreated. More than 90 % of the cases known to date were reported from Asia, mainly from China. The nearest neighbour of M. irregularis is the saprobic species M. hiemalis. The aim of this study was to evaluate the taxonomic position, epidemiology, and intra- and inter-species diversity of M. irregularis based on 21 strains (clinical n = 17) by multilocus analysis using ITS, LSU, RPB1 and RPB2 genes, compared to results of cluster analysis with... |
| Tipo: Article / Letter to the editor |
Palavras-chave: Biodiversity; Chronic cutaneous infection; Epidemiology; Mucor hiemalis; Mucor irregularis; Mucormycosis; Taxonomy. |
| Ano: 2013 |
URL: http://www.repository.naturalis.nl/record/532463 |
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| Zhang, Y.; Hagen, F.; Stielow, B.; Rodrigues, A.M.; Samerpitak, K.; Zhou, X.; Feng, P.; Yang, L.; Chen, M.; Deng, S.; Li, S.; Liao, W.; Li, R.; Li, F.; Meis, J.F.; Guarro, J.; Teixeira, M.; Al-Zahrani, H.S.; Pires de Camargo, Z.; Zhang, L.; Hoog, G.S. de. |
| Pathology to vertebrate hosts has emerged repeatedly in the order Ophiostomatales. Occasional infections have been observed in Sporothrix mexicana at a low level of virulence, while the main pathogenic species cluster in a derived clade around S. schenckii s.str. In this paper, phylogeny and epidemiology of the members of this clade were investigated for 99 clinical and 36 environmental strains using four genetic loci, viz. rDNA ITS and partial CAL, TEF1, and TEF3; data are compared with amplified fragment length polymorphism (AFLP) genotyping. The four main species of the pathogenic clade were recognised. The species proved to show high degrees of endemicity, which enabled interpretation of literature data where live material or genetic information is... |
| Tipo: Article / Letter to the editor |
Palavras-chave: Epidemiology; Historical biogeography; Phylogeny; Sapronosis; Sporothrix; Sporotrichosis; Transmission routes; Yeast conversion; Zoonosis. |
| Ano: 2015 |
URL: http://www.repository.naturalis.nl/record/588679 |
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