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| Pellosi,Diogo S.; Batistela,Vagner R.; Souza,Vagner R. de; Scarminio,Ieda S.; Caetano,Wilker; Hioka,Noboru. |
| The development of drugs for photodynamic therapy (PDT) is an important area of research due to their growing use in medical applications. Therefore, it is important to develop new bioassay methods for PDT photosensitizers that are inexpensive, easy to handle and highly sensitive to environmental conditions. Xanthene dyes (fluorescein, rose bengal B, erythrosine B and eosin Y) with LED light sources were investigated using Artemia salina as a bioindicator of photodynamic activity. In this study, three factors were investigated: (i) photosensitizers concentration, (ii) the LED irradiation time and (iii) the waiting time between the addition of the photosensitizers and the beginning of the irradiation. To analyze the photo-killing of A. salina, it was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Artemia salina; Factorial design; Photodynamic therapy; Bioassay; Xanthenes. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401267 |
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