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Abiotic stress protection by ecologically abundant dimethylsulfoniopropionate and its natural and synthetic derivatives: insights from B acillus subtilis ArchiMer
Broy, Sebastian; Chen, Chiliang; Hoffmann, Tamara; Brock, Nelson L.; Nau-wagner, Gabriele; Jebbar, Mohamed; Smits, Sander H. J.; Dickschat, Jeroen S.; Bremer, Erhard.
Dimethylsulfoniopropionate (DMSP) is an abundant osmolyte and anti-stress compound produced primarily in marine ecosystems. After its release into the environment, microorganisms can exploit DMSP as a source of sulfur and carbon, or accumulate it as an osmoprotectant. However, import systems for this ecophysiologically important compatible solute, and its stress-protective properties for microorganisms that do not produce it are insufficiently understood. Here we address these questions using a well-characterized set of Bacillus subtilis mutants to chemically profile the influence of DMSP import on stress resistance, the osmostress-adaptive proline pool and on osmotically controlled gene expression. We included in this study the naturally occurring...
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Ano: 2015 URL: https://archimer.ifremer.fr/doc/00242/35302/33910.pdf
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