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Diagnostic value of circulating lncRNA ANRIL and its correlation with coronary artery disease parameters BJMBR
Hu,Yao; Hu,Jing.
This study aimed to detect the expression of the long non-coding RNA (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) and evaluate its correlation with disease risk, stenosis degree, inflammation, as well as overall survival (OS) in coronary artery disease (CAD) patients. A total of 230 patients who underwent diagnostic coronary angiography were consecutively recruited and assigned to CAD group (n=125) or control group (n=105) according to presence or absence of CAD. Gensini score was calculated to assess the severity of coronary artery damage. Plasma samples were collected and the expression ANRIL was detected in all participants. High-sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), and cytokines including tumor...
Tipo: Info:eu-repo/semantics/article Palavras-chave: LncRNA ANRIL; Coronary artery disease; Diagnosis; Disease severity; Inflammatory responses; Overall survival.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000800612
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