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SHIMIZU, Takashi; IIJIMA, Koji; SASADA, Hiroshi; SATO, Eimei; 清水, 隆. |
Angiogenic factors are associated with angiogenesis during follicular development in the mammalian ovary. The aim of the present study was to determine the relationships between the vascular network and mRNA expressions of angiopoietins (Ang)-1, Ang-2 and hepatocyte growth factor (HGF), and their receptors in follicles at different developmental stages during follicular development. Ovaries in gilts were collected 72 h after equine chorionic gonadotropin (eCG, 1250 IU) treatment for histological observation of the capillary network. Granulosa cells and thecal tissues in small (<4 mm), medium (4-5 mm) or large (>5 mm) individual follicles were collected for detection of mRNA expression of HGF, Ang-1 and Ang-2 in granulosa cells, and HGF receptor... |
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Palavras-chave: Follicular Development; Angiogenesis; Angiopoietins; HGF; Pig. |
Ano: 2003 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4055 |
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